Search results for "Surface marker"

showing 4 items of 4 documents

The two faces of tumor-associated macrophages and their clinical significance in colorectal cancer

2019

© 2019 Pinto, Rios, Durães, Ribeiro, Machado, Mantovani, Barbosa, Carneiro and Oliveira. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

0301 basic medicineMaleColorectal cancerprognostic and tumor relapseMacrophages / immunologyhuman macrophage surface markers0302 clinical medicineTumor MicroenvironmentImmunology and AllergyColorectal Neoplasms / mortalityOriginal ResearchAged 80 and overTumor immunomodulationCD68tumor-associated macrophagesTumor-associated macrophagesTumor Microenvironment / immunologyMiddle AgedPrognosis3. Good healthMacrophage polarizationImmunohistochemistryFemaleHuman macrophage surface markerstumor immunomodulationColorectal NeoplasmsInfiltration (medical)lcsh:Immunologic diseases. AllergyAdultmacrophage polarizationImmunologyMacrophage polarizationcolorectal cancerBiologyPrognostic and tumor relapseColorectal Neoplasms / pathology03 medical and health sciencesYoung AdultImmune systemmedicineHumansAgedMacrophagesColorectal Neoplasms / immunologymedicine.diseaseColorectal cancer030104 developmental biologyCancer researchlcsh:RC581-607CD163CD80030215 immunology
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Surface Marker Analysis by Monoclonal Antibodies: A Valuable Technique in Childhood Acute Myeloid Leukemia

1987

A considerable number of monoclonal antibodies (MoAbs) with myeloid activity have been described during the last few years (summarized in [1]). These MoAbs have been applied to the study of normal myeloid differentiation, as well as to the surface marker analysis of acute myeloid leukemia (AML) [2–6]. Although there is a strong tendency for morphological differentiation to correspond to surface antigen differentiation of malignant myeloid cells [2, 3], a recent report has failed to correlate the FAB classification system with immunologic categories of AML [6].

Acute leukemiaMyeloidAcute myeloblastic leukemiamedicine.drug_classbusiness.industryChildhood Acute Myeloid LeukemiaMyeloid leukemiamedicine.diseaseMonoclonal antibodymedicine.anatomical_structureAntigenhemic and lymphatic diseasesImmunologySurface markermedicinebusiness
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Homing and memory patterns of human gammadelta T cells in physiopathological situations.

2004

Vgamma9Vdelta2 are a heterogeneous population of T cells and comprise distinct naive, memory and effector populations that can be distinguished on the basis of surface marker expression and effector functions. We review here these recently studied features of Vgamma9Vdelta2 T lymphocyte biology and the roles they play in infectious and autoimmune diseases.

EffectorImmunologyT lymphocyteBiologymedicine.disease_causeInfectionsLymphocyte ActivationMicrobiologyAutoimmunityAutoimmune DiseasesHeterogeneous populationInfectious DiseasesT-Lymphocyte SubsetsSurface markerImmunologymedicineHumansTuberculosisEffector functionsMalaria FalciparumProtozoal diseaseImmunologic MemoryHoming (hematopoietic)Microbes and infection
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Differences in intercellular communication during clinical relapse and gadolinium-enhanced MRI in patients with relapsing remitting multiple sclerosi…

2018

This study was designed based on the hypothesis that changes in both the levels and surface marker expression of extracellular vesicles (EVs) isolated from the cerebrospinal fluid (CSF) may be associated with the clinical form, disease activity, and severity of multiple sclerosis (MS). The analyzes were performed on subjects affected by MS or other neurological disorders. EVs, which were isolated by ultracentrifugation of CSF samples, were characterized by flow cytometry. A panel of fluorescent antibodies was used to identify the EV origin: CD4, CCR3, CCR5, CD19, and CD200, as well as isolectin IB4. The Mann–Whitney U-test and Kruskal–Wallis test were used for statistical analyzes. EVs isol…

lymphocytes0301 basic medicinePathologymedicine.medical_specialtyNaive B cellmultiple sclerosisCD19lcsh:RC321-57103 medical and health sciencesCellular and Molecular Neuroscience0302 clinical medicineCerebrospinal fluidmedicineMultiple sclerosiSettore BIO/06 - Anatomia Comparata E Citologialcsh:Neurosciences. Biological psychiatry. NeuropsychiatryOriginal ResearchAutoimmune diseaseClinically isolated syndromebiologybusiness.industrysurface markersMultiple sclerosismedicine.disease030104 developmental biologyCerebrospinal fluidbiology.proteinLymphocyteSurface markerAntibodyExtracellular vesicleextracellular vesiclesbusiness030217 neurology & neurosurgeryCD8Neuroscience
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